Executive Director Roy Michael said with over 600 million people and a combined gross domestic product (GDP) of RM2.4 trillion in 2013, ASEAN was the seven largest market.
"Should the trend continue and with the realisation of the ASEAN Economic Community(AEC) by year-end, it has the potential to become the fourth largest market globally by 2050," he added.
He told Bernama, ASEAN was now one of the most open economic regions in the world.
"Significant progress had been made in integrating the economies of the 10-member states under the AEC blueprint," he said.
He also said the Mutual Recognition Arrangement (MRA) amongst ASEAN members would lead to greater workforce mobility and develop more equitable growth in the region.
"The labor expansion and productivity will drive the GDP and make ASEAN the engine of global growth," he added.
Michael was speaking after hosting the ASEAN-US Trade Winds Forum at the Malaysian Embassy here on Wednesday. It was attended by American policy and industry leaders.
The half-day forum is a quarterly event hosted on rotation between ASEAN embassies here to increase understanding between American and ASEAN small and medium enterprises.
Panel discussions included updates on the progress of the AEC, challenges in achieving ASEAN economic integration, and the South China Sea dispute.
Among the guest speakers were Malaysia's ambassador to the United States, Datuk Dr Awang Adek Husin, representatives of the Ministry of International Trade and Industry and the Malaysia External Trade Development Corporation (Matrade).
Also participating were the embassies of Myanmar and the Philippines, the US Department of Commerce, the US Agency for International Development (USAID), the Center of Naval Analysis (CNA), and the US-ASEAN Business Council.
The Trade Commissioner of Matrade New York, Muhd Shahrulmiza Zakaria at the forum, encouraged the American business community to establish new business partnerships with Malaysian companies operating in the ASEAN marketplace.
"American SMEs can also leverage on Malaysia as the base for sourcing activities, and at the same time explore ASEAN's fast growing consumer market. This will be a win-win venture for the US companies," he added.
Meanwhile, MYUSCHAM is hosting an Islamic Finance Conference on Oct 22, themed, "Islamic Capital Market: Inroads into the US", with the tagline, "An Alternative Engine for Growth" in Washington DC.
"The conference will be helmed by Malaysian and American Islamic capital market players and is spearheaded by Datuk Noripah Kamso, Chairman of the MYUSCHAM Islamic Finance Industry Council.
Michael said the conference will be a perfect meeting place for Malaysians and Americans to leverage on opportunities in attracting greater collaboration and cooperation among capital market players.